“Amyloid fibrils are a type of self-assembled proteins/peptides that take on a stacked sheet-like formation. Amyloid fibril aggregates are known to be a cause of several diseases—including Alzheimer’s—and therefore, it is of immense scientific interest to understand how these aggregates can be broken. Some types of amyloid fibrils also play a role in regulation of gene expression in some organisms. It is also thought that the fiber-like formats appearing in these aggregates act as scaffolds on which to cultivate biomaterials. Therefore, a suitable technique for breakdown or “dissociation” of amyloid protein fibrils is critical from the perspective of medical treatment, modification of biological structures and functions, and even biomaterial engineering.”
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